Looking for a cozy, no-fuss dinner idea? This Easy Turkey Tetrazzini is everything you want in a comfort food classic, creamy, cheesy, and perfect for using up leftover turkey. It’s a family favorite that’s ready to hit your table with minimal prep and maximum flavor. For another cozy, home-cooked meals, check out our Marry Me Chicken Mac and Cheese!

A baking dish filled with turkey tetrazzini, a spoon is lifting a serving out of the dish.

What Is Turkey Tetrazzini?

Turkey Tetrazzini is a creamy baked pasta dish made with cooked turkey, spaghetti, mushrooms, and a rich cheese sauce. This version skips the fancy steps and sticks with easy, everyday ingredients, so you can get dinner on the table without the extra effort.

Why You’ll Love Turkey Tetrazzini

You’ll love this Turkey Tetrazzini because it’s truly no-fuss—there’s no need for a roux or complicated sauce; just mix everything together and bake. It’s perfect for busy nights or holiday leftovers, especially since it can be made ahead of time and stored in the fridge until you’re ready to pop it in the oven. It also freezes beautifully, making it a great option for meal prep. And if you like to mix things up, this recipe is easy to customize, add your favorite veggies or swap in a different protein like chicken or ham.

Tips for success

For best results, slightly undercook your pasta before baking to keep it from turning mushy in the oven. If your sauce feels a bit too thick when mixing, you can easily thin it out with a splash of milk or chicken broth. Be sure not to skip the cheese on top, it bakes into a perfectly golden, irresistible crust. And once it’s out of the oven, give the casserole 5 to 10 minutes to rest before serving.

a plate of creamy turkey tetrazzini.

How to Store and Reheat Tetrazzini

  • Refrigerator: Store in an airtight container for up to 4 days.
  • Freezer: Wrap tightly and freeze for up to 3 months. Thaw in fridge before reheating.
  • Reheat: Warm in a 350°F oven, covered with foil, or microwave individual servings.
A baking dish filled with turkey tetrazzini, a spoon is lifting a serving out of the dish.

Turkey Tetrazzini

This easy turkey tetrazzini is creamy, cheesy, and perfect for leftovers, quick to prep and totally comforting.

Ingredients

  • 16 ounces spaghetti, cooked and drained
  • 3 cups cooked turkey, chopped
  • 2 cans (10.5-ounces each) cream of mushroom soup
  • 2 cups sour cream
  • ½ cup chicken broth
  • ¼ cup parmesan cheese, grated
  • 1/2 teaspoon garlic powder
  • ½ teaspoon onion powder
  • 2 cups shredded mozzarella cheese, divided
  • Salt and pepper, to taste
  • parsley, chopped for garnish

Instructions

  • Preheat oven to 350°F. Lightly grease a 9×13-inch baking dish.
  • In a large bowl, combine cooked spaghetti, turkey, soup, sour cream, milk, garlic powder, onion powder, 1 cup mozzarella, and parmesan.
  • Season with salt and pepper. Mix until fully combined.
  • Pour mixture into the prepared dish. Top with remaining mozzarella.
  • Cover with aluminum foil and bake 45 minutes.
  • Remove foil and bake an additional 10-15 minutes, or until cheese is hot and bubbly.
  • Let rest for 5 minutes before garnishing with parsley and serving.

More Casseroles

Baked Ziti

Baked Ziti is a cheesy baked pasta dish that is the perfect comfort food. It is made with three kinds of cheese, ground beef, ziti pasta, and homemade marinara sauce.

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