If you love easy comfort food recipes that practically cook themselves, this Mississippi Pot Roast is a must-try. This cozy staple is made with simple ingredients and is perfect for busy weeknights or lazy weekends. The slow cooker does all the work, and the result is tender, flavorful beef with just the right amount of tang from pepperoncini peppers. If you are looking for more delicious crock pot meals, make sure to check out our slow cooker 2-ingredient pulled pork.

Mississippi Pot Roast in a crock pot.

Why Youโ€™ll Love This Recipe

  • Effortless cooking: Just sear, season, and let your slow cooker take it from there.
  • Incredible flavor: The combination of ranch mix, au jus, butter, and pepperoncini creates a rich, savory sauce.
  • Family-friendly: This recipe makes enough to feed a crowd and can be served in so many different ways.
  • Versatile: Pile it on mashed potatoes, stuff it into sandwiches, or serve it with roasted veggies.

Substitution Ideas

  • Meat: While chuck roast is the classic choice, you can use brisket or round roast if thatโ€™s what you have. Pork shoulder also works for a twist.
  • Pepperoncini: Donโ€™t like too much heat? Swap with banana peppers for a milder flavor.
  • Butter: Salted butter can be used if you prefer; just reduce the added salt.
  • Seasonings: If you donโ€™t have au jus mix, brown gravy mix makes a good replacement.

Common Questions About Mississippi Pot Roast

Is Mississippi Pot Roast spicy?
Not really. Pepperoncini peppers are tangy and slightly zesty, not hot.

Do I need to add liquid?
No extra broth is necessary, the butter and pepperoncini juice create plenty of flavorful liquid as it cooks.

Can I make it in the oven instead?
Yes. Place everything in a Dutch oven, cover, and bake at 275ยฐF for about 4-5 hours until tender.

Mississippi Pot Roast served over mashed potatoes.

Tips and Tricks

  • Sear the meat: While optional, searing locks in flavor and creates a richer sauce.
  • Donโ€™t skip the juice: The pepperoncini brine is what gives this roast its signature tang.
  • Cook low and slow: Resist the urge to speed things up, low for 8 hours yields the best, fall-apart beef.
  • Serving ideas: Try it over mashed potatoes, rice, or even egg noodles. Leftovers make amazing sandwiches.

Storage, Freezing, and Reheating

  • Refrigerator: Store in an airtight container for up to 4 days.
  • Freezer: Freeze in portions with some of the juices for up to 3 months. Thaw overnight in the fridge before reheating.
  • Reheating: Warm gently in a skillet or microwave with a splash of beef broth to keep it juicy.
Mississippi Pot Roast served over mashed potatoes.

Mississippi Pot Roast

Prep Time 10 minutes
Cook Time 8 hours
Total Time 8 hours 10 minutes
Tender Mississippi Pot Roast made in the slow cooker with ranch, au jus, butter, and pepperoncini for the ultimate comfort meal.

Ingredients

  • 3-4 pound chuck roast
  • 1 teaspoon kosher salt
  • ยฝ teaspoon black pepper
  • 1 tablespoon vegetable oil
  • 1 packet (1 ounce) dry ranch dressing mix
  • 1 packet (1 ounce) dry au jus gravy mix
  • ยผ cup unsalted butter, sliced
  • 8 large pepperoncini peppers
  • 2 tablespoons juice from the pepperoncini jar
  • salt and pepper, to taste

Instructions

  • Season both sides of the roast lightly with kosher salt and ground black pepper.
  • In a large skillet over medium-high heat, heat vegetable oil until shimmering. Add the roast and sear for about 2โ€“3 minutes on each side, until a golden crust forms.
  • Transfer the seared roast to the slow cooker.
  • Sprinkle ranch dressing mix and au jus gravy mix evenly over the top of the roast.
  • Place the sliced butter on top of the seasonings.
  • Add whole pepperoncini peppers around and on top of the roast. Pour pepperoncini juice over everything.
  • Cover and cook on low for 8 hours, or until the meat is fall-apart tender and easily shredded with a fork.
  • Shred the meat in the slow cooker using two forks, mix gently to coat with the juices, and serve warm over mashed potatoes, rice, or noodles.

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